Breath for DX
Making every breath count for diagnosis
New approaches to the respiratory diseases
Respiratory infections resulted in >7 million deaths in 2020 and were responsible for 7 of the last 9 pandemics, causing trillions of €s in economic losses.
Despite the importance of early detection for individual health and pandemic control, flawed sampling methods for respiratory infections limit the impact of highly-sensitive molecular diagnostics. BreathForDx’s overall goal is to tackle this problem by establishing exhaled breath aerosol (XBA) as a novel, evidence-based sample for respiratory infections in three use cases: diagnosis, screening, and antimicrobial resistance, using tuberculosis (TB) as a model infection.
workstream & workpackages
The BreathForDx project aims to demonstrate the potential of XBA as a new sample type for airborne pathogens by optimizing and assessing sampling devices, conducting clinical studies, and evaluating large-scale feasibility and population-level impact.